Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)
2529.24 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - TR2-C52H7
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ug
Parameters
| Additional information | Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is also known as TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2), Death receptor 5 (DR5), CD262, KILLER, is a member of the TNF-receptor superfamily, and contains an intracellular death domain. TNFRSF10B / DR-5 is widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines. TRAILR2 / CD262 / DR5 is the receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD (a death domain containing adaptor protein) of TRAIL-R2 / TNFRSF10B recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. CD262 / DR5 Promotes the activation of NF-kappa-B. DR5 is essential for ER stress-induced apoptosis and is regulated by p53/TP53. |
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| Storage and shipping | -20℃ RT |
TR2-C52H7
Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)
Cynomolgus TRAIL R2, His Tag (TR2-C52H7) is expressed from human 293 cells (HEK293). It contains AA Ile 58 - Ser 212 (Accession # A0A2K5TXK0-1).
2529.24 €
IMNCYTRAILR2DR5TNFRSF10BRHISLY100UG
Monkey Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Recombinant Protein His Tag Lyophilized
Monkey Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Recombinant Protein His Tag Lyophilized
1271.5 €
FGB-C52H6
Cynomolgus FGF R2 (IIIb) protein, His Tag (MALS verified)
Cynomolgus FGFR2 (IIIb), His Tag (FGB-C52H6) is expressed from human 293 cells (HEK293). It contains AA Pro 154 - Lys 368 (Accession # A0A2K5TL84-1).
3562.56 €
IGR-C5225-1mg
Cynomolgus IGF-I R / CD221 Protein, His Tag (MALS verified)
Cynomolgus IGF-I R, His Tag (IGR-C5225) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Asn 932 (Accession # G7P9I7-1).
3562.56 €
B73-C52Ha
Cynomolgus B7-H3 (4Ig) / CD276 Protein, His Tag (MALS verified)
Cynomolgus B7-H3 (4Ig) Protein, His Tag (B73-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Glu 465 (Accession # XP_015308534.1).
3078.6 €
B73-C52Ha-100ug
Cynomolgus B7-H3 (4Ig) / CD276 Protein, His Tag (MALS verified)
Cynomolgus B7-H3 (4Ig) Protein, His Tag (B73-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Glu 465 (Accession # XP_015308534.1).
593.4 €
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