Cynomolgus TNFSF11 / RANKL / CD254 Protein, Fc Tag
658.8 EUR
658.8 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - RAL-C5263
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 1mg
Parameters
| Additional information | Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is known as a type II membrane protein and is a member of the tumor necrosis factor (TNF) superfamily. RANKL, through its ability to stimulate osteoclast formation and activity, is a critical mediator of bone resorption and overall bone density. Some findings also suggestion some cancer cells, particularly prostate cancer cells, can activate an increase in bone remodeling and ultimately increase overall bone production.[17] This increase in bone remodeling and bone production increases the overall growth of bone metastasizes. The overall control of bone remodeling is regulated by the binding of RANKL with its receptor or its decoy receptor, respectively, RANK and OPG. |
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| Storage and shipping | -20℃ RT |
RAL-C5263
Cynomolgus TNFSF11 / RANKL / CD254 Protein, Fc Tag
Cynomolgus TNFSF11 Protein, Fc Tag (RAL-C5263) is expressed from human 293 cells (HEK293). It contains AA Gly 136 - Asp 317 (Accession # A0A7N9DBU4).
658.8 €
RAL-C5243
Cynomolgus TNFSF11 / RANKL / CD254 Protein, His Tag, active trimer (MALS verified)
Cynomolgus TNFSF11 Protein, His Tag (RAL-C5243) is expressed from human 293 cells (HEK293). It contains AA Gly 136 - Asp 317 (Accession # A0A7N9DBU4).
3902.64 €
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