CD103 Mouse, Antibody
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On request
quantity
Produktdetaljer
Katalognummer: 137 - GWB-4F625C
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 0.5 mg
Parameters
| Additional information | CD103 Mouse, Antibody was previously known under catalogue number 20-251-401327 was previously known under catalogue number 20-251-401327 |
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RD21011F-100Tests
APC Anti-Mouse CD103 Antibody
CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
181 €
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