BMP10 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03707)

OKCD03707

BMP10 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03707)

Description of target: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines .;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.156 ng/mL

2005.6 €

OKCD03707-96W

OKCD03707-96W - BMP10 Chemi-Luminescent ELISA Kit (Mouse)

1432 €

OKCD03326

BMP2 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03326)

Description of target: Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.6 pg/mL

2005.6 €

EBB0396

Bovine BMP10 ELISA Kit

1087.8 €

EPB0396

Porcine BMP10 ELISA Kit

1087.8 €

ECKB0396

Chicken BMP10 ELISA Kit

1087.8 €