
Katalognummer: 716 - MU1-H82E5
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 25ug
| Additional information | Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces. |
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| Storage and shipping | -20℃ RT |

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