Biotinylated Human IL-4 R alpha / CD124 Protein, Avitag™,His Tag (MALS verified)
2215.32 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - ILR-H82E9
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 25ug
Parameters
| Additional information | IL-4 is a pleiotropic cytokine produced by activated Th2 cells and mast cells, and plays a pivotal role in immune responses. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells. Hematopoietic cellular responses to IL-4 are mediated by a high affinity receptor complex comprised of the 140 kDa IL4Rα (CD124)subunit and the 70 kDa common cytokine γc chain (CD132).Interleukin 4 Receptor (IL4R) also known as CD124, IL4Rα and BSF receptor, is a type I cytokine receptor produced by activated Th2 cells and mast cells, and plays an important role in Th2-biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. A soluble form of the encoded IL4R protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. IL4R can alternatively associate with IL13Ra1 to form the type II receptor which is responsive to both IL4 and IL13. Interleukin-4 receptor has been shown to interact with SHC1. |
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| Storage and shipping | -20℃ RT |
ILR-H82E9
Biotinylated Human IL-4 R alpha / CD124 Protein, Avitag™,His Tag (MALS verified)
Biotinylated Human IL-4 R alpha, Avitag,His Tag (ILR-H82E9) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # NP_000409.1).
2215.32 €
ILR-H82F4
Biotinylated Human IL-4 R alpha / CD124 Protein, Fc,Avitag™ (MALS verified)
Biotinylated Human IL-4 R alpha, Fc,Avitag (ILR-H82F4) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # P24394-1).
2215.32 €
ILA-H82F5
Biotinylated Human IL-5 R alpha / CD125 Protein, Avitag™,Fc Tag (MALS verified)
Biotinylated Human IL-5 R alpha Protein, Avitag,Fc Tag (ILA-H82F5) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Trp 342 (Accession # Q01344-1).
2019.12 €
NKD-H82Q3
Biotinylated Human NKG2D / CD314 Protein, Avitag™,His Tag (MALS verified)
Biotinylated Human NKG2D Protein, Avitag,His Tag (NKD-H82Q3) is expressed from human 293 cells (HEK293). It contains AA Ile 73 - Val 216 (Accession # P26718-1).
2110.68 €
CT4-H82E3
Biotinylated Human CTLA-4 Protein, His,Avitag™ (MALS verified)
Biotinylated Human CTLA-4, His,Avitag (CT4-H82E3) is expressed from human 293 cells (HEK293). It contains AA Ala 37 - Phe 162 (Accession # P16410-1).
3837.24 €
CD0-H82E6
Biotinylated Human CD30 / TNFRSF8 Protein, Avitag™,His Tag (MALS verified)
Biotinylated Human CD30, Avitag,His Tag (CD0-H82E6) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
2215.32 €
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