Biotinylated Human HVEM / TNFRSF14 Protein, Fc,Avitag™ (MALS verified)
658.8 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - HVM-H82F6
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 200ug
Parameters
| Additional information | Herpesvirus entry mediator (HVEM) is also known as TNFRSF14, TR2 (TNF receptorlike molecule) and ATAR (another TRAF associated receptor), is a type I membrane protein belonging to the TNF/NGF receptor superfamily. HVEM expression has been detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. The extracellular domain of HVEM has been shown to interact directly with the herpes simplex virus envelope glycoprotein D (gD). Two TNF superfamily ligands, including the secreted TNFβ (lymphotoxin α) and the membrane protein LIGHT (lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), have been shown to be the cellular ligands for HVEM. Besides HVEM, LIGHT can also interact with LTβR, the receptor for lymphotoxin αβ heterotrimer. The role of the HVEM LIGHT /LTβ receptor ligand pair in immune function and herpesvirus pathobiology remains to be elucidated. |
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| Storage and shipping | -20℃ RT |
HVM-H82F6
Biotinylated Human HVEM / TNFRSF14 Protein, Fc,Avitag™ (MALS verified)
Biotinylated Human HVEM, Fc,Avitag (HVM-H82F6) is expressed from human 293 cells (HEK293). It contains AA Leu 39 - Val 202 (Accession # Q92956-1).
658.8 €
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