Biotinylated Human GDF-15 / MIC-1 Protein, Avitag™, Fc Tag (MALS verified)

Biotinylated Human GDF-15 / MIC-1 Protein, Avitag™, Fc Tag (MALS verified)

2019.12 EUR

2019.12 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 716 - GD5-H82F9

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

ACROBIOSYSTEMSGentaur

Storlek: 25ug

Parameters

Additional informationGrowth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1). Expression of MIC-1 mRNA in monocytoid cells is up-regulated by a variety of stimuli associated with activation, including interleukin 1β, tumor necrosis factor α (TNF-α), interleukin 2, and macrophage colony-stimulating factor but not interferon γ, or lipopolysaccharide (LPS). It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk. Increased GDF-15 levels are associated with cardiovascular diseases such as hypertrophy, heart failure, atherosclerosis, endothelial dysfunction, obesity, insulin resistance, diabetes, and chronic kidney diseases in diabetes. Increased GDF-15 level is linked with the progression and prognosis of the disease condition.
Storage and shipping-20℃ RT