Biotinylated Human EphA2 Protein, His,Avitag™ (MALS verified)

Biotinylated Human EphA2 Protein, His,Avitag™ (MALS verified)

658.8 EUR

658.8 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 716 - EP2-H82E4

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

ACROBIOSYSTEMSGentaur

Storlek: 200ug

Parameters

Additional informationReceptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
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