Biotinylated Human DDR1 Protein, His,Avitag™ (MALS verified)

Biotinylated Human DDR1 Protein, His,Avitag™ (MALS verified)

2215.32 EUR

2215.32 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 716 - DD1-H82E9

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

ACROBIOSYSTEMSGentaur

Storlek: 25ug

Parameters

Additional informationDiscoidin domain receptor 1 (DDR1) is a member of DDRs, which are members of the receptor tyrosine kinase (RTK). Upon collagen binding, DDR1 undergoes tyrosine autophosphorylation, which consequently triggers downstream genetic and cellular pathways and plays critical roles in the regulation of cellular morphogenesis, differentiation, proliferation, adhesion, migration, and invasion. Research shows that DDR1 is closely related to various human diseases including cancer, fibrosis, atherosclerosis, and other inflammatory disorders. New generation DDR1 inhibitors targeting the allosteric sites outside of the canonical ATP-binding pocket or extracellular domain (allosteric inhibitors) may offer a new opportunity for selective DDR1 inhibition therapy development.
Storage and shipping-20℃ RT