Biotinylated Cynomolgus GUCY2C / Guanylyl cyclase C Protein, His,Avitag™ (MALS verified)

Biotinylated Cynomolgus GUCY2C / Guanylyl cyclase C Protein, His,Avitag™ (MALS verified)

2110.68 EUR

2110.68 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 716 - GUC-C82E9

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

ACROBIOSYSTEMSGentaur

Storlek: 25ug

Parameters

Additional informationGUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.
Storage and shipping-20℃ RT