Bag3 Polyclonal Antibody, Biotin Conjugated

A55869

Bag3 Polyclonal Antibody, Biotin Conjugated

589 €

A55869-050

Bag3 Polyclonal Antibody, Biotin Conjugated

613.75 €

A55869-100

Bag3 Polyclonal Antibody, Biotin Conjugated

795.25 €

MBS8569514-01mLAF610

BAG3 Polyclonal Antibody

905.38 €

MBS8569514-01mLAF635

BAG3 Polyclonal Antibody

905.38 €

RD218208A-120uL

BAG3 Polyclonal Antibody

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

181 €