Arrestin-Beta-2 Monoclonal Antibody

Arrestin-Beta-2 Monoclonal Antibody

480 EUR

480 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 965 - JOT-MCA0186-100ul

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

JotbodyGentaur

Storlek: 100ul

Parameters

Additional informationMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.