anti-SPATA5L1

YF-PA20725

anti-SPATA5L1

Rabbit polyclonal to SPATA5L1

875.4 €

ER1901-68

Anti-SPATA5L1 Antibody

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization.

433.5 €

EM1901-35

Anti-SPATA5L1 Antibody [16A4]

To date, there have been several linkage studies to identify genetic loci determining renal function in individuals with renal disease or in the normal population. Puppala et al. suggested candidate regions including 2q36.3 and 9q21.31–q21.33 in the Mexican–American population, and Schelling et al. reported the 1q43, 7q36.1, 8q13.3, and 18q23.3 regions using multiethnic diabetic populations. There are several additional regions that have been suggested from other linkage studies, including 7p15.3–p13, 12p12.2, and 16q12.2–16q23.1. In recent years, researchers have tried to determine in more detail the genetic basis of the estimated GFR (eGFR) through genome-wide association studies (GWAS), and have begun suggesting some genes or variants as determinants of eGFR or chronic kidney disease. These studies, based on a large number of samples, have identified several variants showing a high level of significance and reproducibility near or within genes including UMOD, SHROOM3, GATM, and SPATA5L1.

465 €

A17005-1

Anti-SPATA20 Antibody Picoband™

Western blot, 0.25-0.5 μg/ml, Human, Mouse;Flow Cytometry, 1-3 μg/1x10⁶ cells, Human;Direct ELISA, 0.1-0.5 μg/ml, Human

381 €

A09906-1

Anti-SPATA18 Antibody Picoband™

Western blot, 0.25-0.5 μg/ml, Human;_x000D_Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human;_x000D_Flow Cytometry, 1-3 μg/1x10⁶ cells, Human;_x000D_Direct ELISA, 0.1-0.5 μg/ml, Human

381 €

MBS8109037-01mL

Anti-SPATA20 Antibody, Rabbit Polyclonal

567.5 €