![Anti-Scavenging Receptor SR-BI Antibody [SR37-06]](/images/no-image-product-box.jpg "Anti-Scavenging Receptor SR-BI Antibody [SR37-06]")
Anti-Scavenging Receptor SR-BI Antibody [SR37-06]
496.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 992 - ET1602-32
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ul
Parameters
| Additional information | Synthetic peptide within Human SRB1 aa 81-130 / 552. |
|---|---|
| Storage and shipping | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
ET1602-32
Anti-Scavenging Receptor SR-BI Antibody [SR37-06]
The macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells. SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis. SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine. SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors. Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
496.5 €
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