Anti-Phospho-p53 (S15) antibody
504.6 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 665 - STJ90365
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 200 µl
STJ11101082
Anti-Phospho-p53-S15 antibody
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
857.4 €
STJ90365
Anti-Phospho-p53 (S15) antibody
p53 is a protein encoded by the TP53 gene which is approximately 43,6 kDa. p53 is localised to the cytoplasm, nucleus and endoplasmic reticulum. It is involved in RET signalling, CDK-mediated phosphorylation and removal of Cdc6, glioma and apoptotic pathways. It is a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. It responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest and changes in metabolism. p53 is expressed ubiquitously. Mutations in the TP53 gene may result in Li-Fraumeni syndrome and choroid plexus papilloma. STJ90365 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous p53 protein which only binds about S15 when S15 is phosphorylated.
504.6 €
STJ11101001
Anti-Phospho-p53-S392 antibody
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
857.4 €
A00016S326
Anti-Phospho-p16 (S326) CDKN2A Antibody
Boster Bio Anti-Phospho-p16 (S326) CDKN2A Antibody catalog # A00016S326. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
720 €
A00173S178
Anti-Phospho-p27 (S178) CDKN1B Antibody
Boster Bio Anti-Phospho-p27 (S178) CDKN1B Antibody catalog # A00173S178. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.
720 €
A04136S113
Anti-Phospho-p23 (S113) PTGES3 Antibody
Boster Bio Anti-Phospho-p23 (S113) PTGES3 Antibody catalog # A04136S113. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
720 €
Håll dig uppdaterad! Visa tidigare publikationer
By: Author , 2 Comment
Anaplasmos hos hundar och katter – allt du behöver veta
23 August 2025
By: Author , 2 Comment
Solbränna – hur leker man säkert i solen?
16 August 2025
By: Author , 2 Comment
Biologiska läkemedel – Modernitet inom farmaci
1 August 2025
By: Author , 2 Comment
Icke-steroida antiinflammatoriska läkemedel – viktig information om populära läkemedel
22 July 2025