Anti-Mouse Sonic Hedgehog (Shh) C-terminal Antibody

103-M269

Anti-Mouse Sonic Hedgehog (Shh) C-terminal Antibody

Human Shh cDNA encodes a 462 amino acid (aa) residue (45 kDa) precursor protein with a 23 aa signal peptide. An autocatalytic cleavage reaction yields a 19 kDa (residues 24 - 197) amino-terminal fragment (Shh-N), and a 25 kDa (residues 198 - 462) carboxy-terminal domain (Shh-C). The N-terminal domain retains all known signaling capabilities, while the C-terminal domain is responsible for the intramolecular processing, acting as a cholesterol transferase that covalently transfers the cholesterol molecule to the C-terminus of Shh-N. When Shh is expressed in insect or mammalian cells, a palmitoyl group is also attached to the N-terminal cysteine of Shh-N via an amide linkage.

748.5 €

mAP-0128

Rat Monoclonal anti-mouse Sonic Hedgehog (Shh) C-Terminal fragment

525 €

mAP-5456

Sheep Polyclonal anti-mouse Sonic Hedgehog (Shh C-terminus)

750 €

abx102255-50ug

Hedgehog Homolog, Sonic (SHH) Antibody

622.36 €

abx102256-100l

Sonic Hedgehog Protein (SHH) Antibody

462.25 €

abx102256-100ug

Hedgehog Homolog, Sonic (SHH) Antibody

802.18 €