Katalognummer: 209 - 101-M713
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 100 µg
102-P37
Interleukin 7 (IL-7), previously known as pre-B-cell growth factor and lymphopoietin-1, is expressed by adherent stromal cells from various tissues. Mouse IL-7 has approximately 65% amino acid sequence identity with human IL-7 and both proteins exhibit cross-species activity.
101-M07
Interleukin 7 (IL-7), previously known as pre-B-cell growth factor and lymphopoietin-1, is expressed by adherent stromal cells from various tissues. Mouse IL-7 has approximately 65% amino acid sequence identity with human IL-7 and both proteins exhibit cross-species activity.
101-M713
Interleukin 7 (IL-7), previously known as pre-B-cell growth factor and lymphopoietin-1, is expressed by adherent stromal cells from various tissues. Mouse IL-7 has approximately 65% amino acid sequence identity with human IL-7 and both proteins exhibit cross-species activity.
101-M467
Two distinct types of receptors that bind the pleiotropic cytokines IL-1 alpha and IL-1 beta have been described. The IL-1 receptor Type I is an 80 kDa transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. IL-1 receptor Type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and, endothelial cells. Both receptors are members of the immunoglobulin superfamily and show approximately 28% sequence similarity in their extracellular domains. The two receptor types do not heterodimerize in a receptor complex. IL-1 RII has a short cytoplasmic domain and does not transduce IL-1 signals. In addition to the membrane-bound form of IL-1 RII, a naturally-occurring soluble form of IL-1 RII has been described. It has been suggested that the Type II receptor, either as the membrane-bound or as the soluble form, serves as a decoy for IL-1 and inhibits IL-1 action by blocking the binding of IL-1 to the signaling Type I receptor complex. Recombinant IL-1 soluble receptor type II is a potent antagonist of IL-1 action.
101-M468
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. IL-1 Rrp2, also known as IL-1 R6, is a transmembrane protein belonging to the IL-1 receptor family. It is a ligand binding subunit that associates with IL-1 RAcP to form a functional receptor complex for IL-1F6, IL-1F8, and IL-1F9.
101-M469
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. Interleukin 1 receptor accessory protein-like 1 (IL-1 RAPL1), also known as IL-1 R8, Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL-1 receptor-related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily.

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