Anti-GAPDH Antibody

LF-MA30032

anti-GAPDH (1A10)

Mouse Monoclonal to GAPDH

823.2 €

A00227

Anti-GAPDH Antibody

679.2 €

ER1901-65

Anti-GAPDH Antibody

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine ​​S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3- phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammatio n processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

433.5 €

MBS8242015-01mL

Anti-GAPDH Antibody

510.12 €

MBS8242015-02mL

Anti-GAPDH Antibody

612.12 €

MBS8242015-5x02mL

Anti-GAPDH Antibody

1995.5 €