Anti-CXCR3 antibody (DM208), Rabbit mAb

MBS188975-001mg

Anti-CXCR3 antibody (DM208), Rabbit mAb

516.5 €

MBS188975-01mg

Anti-CXCR3 antibody (DM208), Rabbit mAb

962.75 €

MBS188975-5x01mg

Anti-CXCR3 antibody (DM208), Rabbit mAb

3321.5 €

ER1802-28

Anti-CXCR4 Antibody

The C-X-C or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemo-attractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB and CXCR-4 (also known as LESTR or fusin). CXCR-4 is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. CXCR-4 has been identified as the major co-receptor for T-tropic HIV-1 and SDF-1 has been shown to inhibit HIV-1 infection.

433.5 €

MBS4153363-01mL

Anti-CXCR4 Antibody

879.88 €

MBS4153363-5x01mL

Anti-CXCR4 Antibody

2990 €