3-Hydroxy Nevirapine
1243.5 EUR
1243.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 572 - H948630
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 0.5mg
Parameters
| Additional information | C₁₅H₁₄N₄O₂ |
|---|---|
| Storage and shipping | RT |
HY-148642
12-Hydroxynevirapine
12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine (HY-10570). Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine[1][2].
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