TTR mouse Monoclonal Antibody(6E5)

TTR mouse Monoclonal Antibody(6E5)

366 EUR

366 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 965 - JOT-MCA1251-50ul

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

JotbodyGentaur

Storlek: 50ul

Parameters

Additional informationThis gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.