STAT3 Reporter (Luc) - HEK293 Cell line (Puromycin)
5802.45 €
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Catalog number: 421 - 79800-P
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 2 vials
79800-P
STAT3 Reporter (Luc) - HEK293 Cell line (Puromycin)
The STAT3 Reporter (Luc)-HEK293 cell line is designed for monitoring STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines and growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.
5802.45 €
60656
GAL4 Reporter (Luc)-HEK293 Cell Line
The GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of a multimerized GAL4 upstream activation sequence (UAS) stably integrated into HEK293 cells. The cell line does not contain any exogenous activators of the GAL4 reporter and can be used alongside BPS Cat. #60655 as a control.
1810.42 €
60650
NF-κB reporter (Luc) - HEK293 Cell line
The NF-κB reporter (Luc) HEK293 cell line is designed to monitor nuclear factor Kappa B (NF-κB) activity. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been functionally validated in response to human TNF-α, IL-1β, and IL-17.
2219.47 €
78589
GIPR/CRE Luciferase Reporter HEK293 Cell Line
Recombinant HEK293 cells expressing the firefly luciferase gene under the control of cAMP response element (CRE), and with forced expression of human GIPR (Gastric Inhibitory Polypeptide receptor; NM_000164.4). Activation of GIPR in these cells can be monitored by measuring luciferase activity._x000D_The functionality of the GIPR/CRE Luciferase Reporter HEK293 Cell Line was validated in a dose-response assay using agonists gastric inhibitory peptide (GIP) and tirzepatide hydrochloride. These agonists induce luciferase activity in a dose-dependent manner as depicted in Figure 1._x000D_<p style="text-align: center;"><img src="{{media url="wysiwyg/Cell_Lines/78589.jpg"}}" alt="" width="530" height="301" />_x000D_Figure 1. Illustration of the GIPR/CRE Luciferase Reporter HEK293 Cell line.
15460.58 €
79380
CSF1R / SRE - Reporter HEK293 Recombinant Cell Line
The CSF1R SRE HEK293 recombinant cell line has been transfected with full-length human CSF1R cDNA (NP_005202) under a CMV promoter for high constitutive expression. The SRE-luciferase reporter is also stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of the Serum Response Element upstream of a minimal promoter. Upon ligand binding, active CSF1R will initiate the MAPK/ERK signaling pathway, leading to expression of the SRE-controlled luciferase reporter.
16596.83 €
79387
VEGFR2 / NFAT Reporter - HEK293 Recombinant Cell Line
Recombinant HEK-293 cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human VEGFR2 (Human Vascular Endothelial Growth Factor Receptor 2; KDR, FLK1; ref seq. NM_002253.1).