Catalog number: 535 - cAP-0004RFP
Product Category: Business & Industrial > Science & Laboratory
Size: 1Frozen Vial
ABC-TC3476
Microvascular endothelial cells line blood vessels and contribute to many biological processes such as angiogenesis, coagulation, trafficking of lymphocytes, and the inflammatory response. Microvascular endothelial cells are diverse and have specific cellular characteristics and functions depending on the organ/tissue in which they are found. Adipose tissue is unique because it has the capacity to continually grow throughout adult life. It thus has a high occurrence of angiogenesis in order to provide the extensive vascularization require for adipose tissue. Studies have shown that angiogenesis precedes adipogenesis, implying that microvascular endothelial cells influence the proliferation of preadipocytes. Microvascular endothelial cell growth is at the same time stimulated by adipocyte secreted VEGG, suggesting a complex paracrine relationships between microvascular endothelial cells and preadipocytes during tissue development.HAMEC from Gentaur Research Laboratories are isolated from human adipose tissue. HAMEC are cryopreserved after purification and delivered frozen. Each vial contains 1 x 10^6 cells in 1 ml volume. HAMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM) and by uptake of DiI-Ac-LDL. HAMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAMEC are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.
ABC-TC3479
The adrenal gland plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid and androgen hormones. The secreted steroids arise from three zones that form the adrenal gland: the zona glomerulosa, zona fasciculate, and zona reticularis. Microvascular endothelial cells line the blood vessels and contribute to many biological processes such as hemostasis, coagulation, trafficking of lymphocytes, and the inflammatory response. Microvascular endothelial cells (MEC) are of importance in the adrenal gland for their regulatory function on the secretion of adrenal hormones. Studies have shown that factors secreted from HAdMEC, such as endothelin-1, nitric oxide, adrenomedullin and PAMP affect aldosterone secretion. HAdMEC differ from MECs from different organs in function and phenotype. For example, compared to brain MEC and liver MEC, adrenal MEC are highly resistant to glucocorticoid-induced cytotoxicity showing that MECs are specialized to the tissues they belong to. HAdMEC from Gentaur Research Laboratories are isolated from human adrenal tissue. HAdMEC are cryopreserved at passage one and delivered frozen. Each vial contains 5×10 5 cells in 1 ml volume. HAdMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CED31 (P-CAM). HAdMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAdMEC are guaranteed to further culture for 15 population doublings in the conditions provided by Gentaur Research Laboratories
ABC-TC3513
The walls of capillaries are composed of a single layer of microvascular endothe-lial cells. These cells differ in morphology and other properties depending on the tissues the capillaries supply. Therefore, Gentaur offers a range of Microvascular Endothelial Cells produced at Gentaur's cell culture facility from normal human tissues of different origins.Shortly after isolation, all Gentaur Microvascular Endothelial Cells are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing.Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur.