Catalog number: 994 - GF4
Product Category: Business & Industrial > Science & Laboratory
Size: 1ml frozen Vial
ABC-TC3614
Endothelial cells lining the microvasculature are known to play a critical gatekeeper role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation.
ABC-TC3656
Endothelial cells lining the microvasculature are known to play a critical "gatekeeper" role in the inflammatory process through their ability to recruit circulating immune cells into tissues and foci of inflammation. Studies show that intestinal microvascular endothelial cells (IMEC) exhibit a strong immune response to LPS challenge and play a critical regulatory role in gut inflammation. Pharmacological inhibition of NOS in activated HIMEC resulted in a significant increase in leukocytes binding. Gene expression profile study reveals that intestinal endothelial cells express biotinidase, which is involved in biotin recycling. The in vitro culture of HIMEC enabled scientists to perform systematic analyses of the cytokine profiles with regard to mRNA expression and protein secretion, and to compare such data with cytokine profiles concomitantly displayed by other endothelial cells.HIMEC from Gentaur Research Laboratories are isolated from human intestinal tissue. HIMEC are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HIMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM) and by uptake of DiI-Ac-LDL. HIMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HIMEC are guaranteed to further culture in the conditions provided by Gentaur Research Laboratories.
ABC-TC3696
Vascular endothelial cells line the blood vessels and contribute to many biological processes such as hematosis, coagulation, trafficking of lymphocytes, and the inflammatory response. The endothelial cell is of primary importance in the extravasation of leukocytes from the circulation into sites of tissue inflammation. In the case of mastitis, the magnitude and duration of inflammation can be related to such parameters as endothelial adhesion molecules expression, cytokine secretion, as well as changes in vascular permeability. Histological study demonstrates that mammary microvasculature is a prominent feature of intralobular tissue and the endothelial cells play an important role in the study of mastitis and associated mammary gland immunopathology. HMMEC from Gentaur Research Laboratories are isolated from human breast tissue. HMMEC are cryopreserved after purification and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HMMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM) and by uptake of DiI-Ac-LDL. HMMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HMMEC are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.