RecombinantOSM,Mouse(HEK293-expressed)
594.6 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0326
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10μg
Parameters
| Additional information | Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi’s sarcoma cells. OSM signals through two types of receptors; one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial. |
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BK0326
RecombinantOSM,Mouse(HEK293-expressed)
ED50 < 0.4 ng/ml, measured in a cell proliferation assay using NIH-3T3 cells.
594.6 €
BK0326
RecombinantOSM,Mouse(HEK293-expressed)
ED50 < 0.4 ng/ml, measured in a cell proliferation assay using NIH-3T3 cells.
228 €
BK0148
RecombinantOSM,Mouse
ED50 < 10 ng/mL, measured by a cell proliferation assay using Rat Embryo Brain cells, corresponding to a specific activity of > 1× 10ˆ5 units/mg.
594.6 €
BK0253
RecombinantIL-6,Human(CHO-expressed)
ED50 < 0.06 ng/ml, measured in a cell proliferation assay using 7TD1 cells.
406.5 €
BK0253
RecombinantIL-6,Human(CHO-expressed)
ED50 < 0.06 ng/ml, measured in a cell proliferation assay using 7TD1 cells.
132 €
96-519
LIF Recombinant Protein (HEK293 Expressed)
Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.
832.9 €
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