RecombinantIL-2Rα,His,Human
453 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0314
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10μg
Parameters
| Additional information | Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to the cytokine IL-2. The IL-2R is made up of 3 subunits - alpha (α), beta (β) and gamma (γ). The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. The β and γ chains of the IL-2R are members of the type I cytokine receptor family. IL-2R has a high binding affinity to IL-2 and is expressed by antigen-activated T lymphocytes (T cells). IL-2 Rα is also known as CD25, p55, and Tac (activated T cell) antigen.Recombinant Human Interleukin-2 Receptor α (IL-2 R α), His produced in HEK 293 cells is a polypeptide chain containing 205 amino acids. A fully biologically active molecule, rhIL-2 R α has a molecular mass of 42 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript. |
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BK0314
RecombinantIL-2Rα,His,Human
Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, ED50 for this effect is < 1.5 µg/ml.
453 €
BK0314
RecombinantIL-2Rα,His,Human
Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, ED50 for this effect is < 1.5 µg/ml.
132 €
BK0248
RecombinantIL-5Rα,Human
ED50 <0.2 ng/ml, measured in a cell proliferation assay using TF-1 cells in the presence of 1 ng/ml human IL-5.
594.6 €
BK0107
RecombinantIL-5,Mouse
ED50 < 2.0 ng/ml, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 5.0× 10ˆ5 units/mg.
406.5 €
BK0107
RecombinantIL-5,Mouse
ED50 < 2.0 ng/ml, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 5.0× 10ˆ5 units/mg.
132 €
BK0109
RecombinantIL-6,Human
ED50 <0.1ng/ml, measured by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells, corresponding to a specific activity of > 1 x 10ˆ7 units/mg.
406.5 €
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