RecombinantIL-1RA,Human(HEK293-expressed)
407.4 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0310
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10μg
Parameters
| Additional information | IL-1 Receptor Antagonist, also known as IL-1RA, ICIL-1RA, IRAP and IL-1RN, is a member of the interleukin 1 cytokine family. It is expressed by monocytes, neutrophils, macrophages, epithelial cells and fibroblasts. IL-1RA inhibits the activity of both IL-1alpha and IL-1beta, and modulates a variety of IL-1 related immune and inflammatory responses. It inhibits the activity of IL-1 by binding to the receptor IL-1R1 and preventing its association with the coreceptor IL-1RAP for signaling. Clinical studies are being conducted to investigate the use of IL-1RA in the treatment of sepsis, rheumatoid arthritis and chronic myelogenous leukemia. |
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BK0310
RecombinantIL-1RA,Human(HEK293-expressed)
ED50 < 0.1 μg /ml, measured in a neutralization assay using D10S cells in the presence of 50pg/ml Human IL-1a.
407.4 €
BK0310
RecombinantIL-1RA,Human(HEK293-expressed)
ED50 < 0.1 μg /ml, measured in a neutralization assay using D10S cells in the presence of 50pg/ml Human IL-1a.
132 €
BK0248
RecombinantIL-5Rα,Human
ED50 <0.2 ng/ml, measured in a cell proliferation assay using TF-1 cells in the presence of 1 ng/ml human IL-5.
594.6 €
BK0097
RecombinantIL-1β,Rat
ED50 < 10 pg/ml, measured by a cell proliferation assay using mouse D10S cells, corresponding to a specific activity of > 1.0× 10ˆ8 units/mg.
156 €
BK0105
RecombinantIL-3β,Rat
ED50 < 5 ng/mL, measured by a cell proliferation assay using NFS-60 cells, corresponding to a specific activity of > 2 × 10ˆ5 units/mg.
406.5 €
BK0105
RecombinantIL-3β,Rat
ED50 < 5 ng/mL, measured by a cell proliferation assay using NFS-60 cells, corresponding to a specific activity of > 2 × 10ˆ5 units/mg.
132 €
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