Recombinant Rat IL-1RA protein
418.4 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 772 - CD00109-20ug
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 20ug
Parameters
| Additional information | > 96 % by SDS-PAGE and HPLC analyses. |
|---|---|
| Storage and shipping | -20ºC |
CD00104-10ug
Recombinant Rat IL-33 protein
Interleukin-33 (IL-33), also known as NF-HEV and DVS 27, is a cytokine belonging to the IL-1 superfamily. It is also a proinflammatory protein that may regulate gene transcription and it induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL-33 is constitutively expressed in smooth muscle and airway epithelia and it binds to a high-affinity receptor family member ST2. In vivo administration of mature IL-33 promotes increased production of IL-5, IL-13, IgE, and IgA, as well as splenomegaly and inflammatory infiltration of mucosal tissues. Recombinant rat IL-3 contains 156 amino acid residues and it shares 59 % a.a. and 90 % sequence identity with human and Mouse IL-33.
628.1 €
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