
Katalognummer: 806 - RP00169
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 10μg
| Additional information | SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed on the surface of NK cells, CD8+ T cells, activated B cells, and mature dendritic cells but not in promyelocytic, B-cell lines, or T-cell lines. In human NK cells, activated SLAMF7 transmits signals following association with the adaptor protein EAT-2 . In the absence of EAT-2, SLAMF7 potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins. |
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| Storage and shipping | Store the lyophilized protein at -20°C to -80 °C for long term.;After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |

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