Recombinant Human CCL14 Protein

AP77321

RecombinantHumanCytochromeb-245heavychain(CYBB),partial

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KIF1A-1121H

RecombinantHuman KIF1A Protein, His-tagged

Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.

617.6 €

MBS286194-01mg

RecombinantHumanBeta-2-microglobulin(B2M)protein

797 €

MBS142020-1mg

Recombinant Human HCC-1 (CCL14)

3857 €

MBS142020-5x1mg

Recombinant Human HCC-1 (CCL14)

16288.25 €

Z100305

Recombinant Human HCC-1 (CCL14)

Hemofiltrate C-C chemokine (HCC)-1 is a recently described monocyte chemoattractant. CCL14 (also known as HCC-1) belongs to the CC chemokine family. Its mature propeptide is a low-affinity agonist of CCR1 that is converted to a high-affinity agonist of CCR1 and CCR5 on proteolytic processing by serine proteases. Determination of the amino acid sequence of HCC-1 revealed four cysteine residues in positions characteristic of the C-C chemokine family, and comparison with the sequences of other chemokines revealed that HCC-1 was most homologous to MIP-1a. However, several functional properties of HCC-1 were atypical of chemokines. Unlike other chemokines, HCC-1 was expressed constitutively in a number of tissues and was present at high concentrations in normal human plasma. In addition, HCC-1 was reported not to be chemotactic for leukocytes.

393.5 €