OKCD05815-96W - IL1R1 ELISA Kit (Mouse)
1094.5 EUR
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Katalognummer: 247 - OKCD05815-96W
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 96Wells
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| Additional information | IL1R1 ELISA Kit (Mouse) |
|---|
OKCD05815
IL1R1 ELISA Kit (Mouse) (OKCD05815)
Description of target: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.059 ng/mL
1559.2 €
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