OKCD00751
Description of target: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.3 Publications
 <p>Manually curated information for which there is published experimental evidence.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.11"Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA."_x005F_x005F_x000D_Ikeyama S., Koyama M., Yamaoko M., Sasada R., Miyake M._x005F_x005F_x000D_J. Exp. Med. 177:1231-1237(1993) [PubMed] [Europe PMC] [Abstract]Cited for: ROLE IN CELL MOTILITY AND METASTASIS.Ref.12"CD9-regulated adhesion. Anti-CD9 monoclonal antibody induce pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin."_x005F_x005F_x000D_Masellis-Smith A., Shaw A.R._x005F_x005F_x000D_J. Immunol. 152:2768-2777(1994) [PubMed] [Europe PMC] [Abstract]Cited for: ROLE IN CELL ADHESION.Ref.13"Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusion."_x005F_x005F_x000D_Higginbottom A., Takahashi Y., Bolling L., Coonrod S.A., White J.M., Partridge L.J., Monk P.N._x005F_x005F_x000D_Biochem. Biophys. Res. Commun. 311:208-214(2003) [PubMed] [Europe PMC] [Abstract]Cited for: ROLE IN SPERM-EGG FUSION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 12.5 pg/mL
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