NRG1 Beta 1 Protein, Human, Recombinant (ECD, Fc Tag)

MBS2545728-01mg

Recombinant Human NRG1-beta 1 Protein (EGF Domain, Fc tag)

988.25 €

MBS2545728-1mg

Recombinant Human NRG1-beta 1 Protein (EGF Domain, Fc tag)

5017.25 €

MBS2545728-5x1mg

Recombinant Human NRG1-beta 1 Protein (EGF Domain, Fc tag)

21930.12 €

MBS8120871-5x1mg

NRG1 Beta 1 Protein, Human, Recombinant (EGF Domain, Fc Tag)

12456.88 €

IHUNRG1B1RTFLY50UG

Human NRG1?beta 1 Recombinant Protein Tag Free Lyophilized

Human NRG1?beta 1 Recombinant Protein Tag Free Lyophilized

1211.5 €

91-595

NRG1‑beta 1 Recombinant Protein

Pro-neuregulin-1,Neuregulin-1 beta 1（NRG1） is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

1012.45 €