Nrf2 Luciferase Report Cell Line-MCF7
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Catalog number: 870 - ABC-RC001D
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
ABC-RC001D
Nrf2 Luciferase Report Cell Line-MCF7
The Nrf2 Luciferase Reporter cell line is a stably transfected MCF7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the antioxidant response element (ARE). ARE is known to regulate expression and induction of various detoxifying enzyme genes in response to antioxidants and xenobiotics, and is primarily regulated by the Keap1-Nrf2 pathway in which induction and nuclear translocation of Nrf2 mediated by antioxidants and xenobiotics results in the binding of Nrf2 to ARE leading to the expression of defensive genes.
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ABC-RC156D
Luciferase(Puromycin) Report Cell Line-MCF7
Transformed from human breast cancer cell line, MCF7 adhesive cell using lentivirus expressing firefly luciferase gene. The Luciferase was expressed under the enhanced EF1a promoter. The Puromycin marker was expressed under Rsv promoter. The cell line demonstrates high level of bioluminescence signal via firefly luciferase assay.
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ABC-RC116D
Hippo Pathway TEAD Report Cell Line-MCF7
The TEAD Reporter andndash; MCF7 cell line contains the firefly luciferase gene under the control of TEAD responsive elements stably integrated into the human breast cancer cell line, MCF7. Inside the cells, basal unphosphorylated YAP/TAZ remains in the nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter by the activators of the Hippo pathway.
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ABC-RC159D
Luciferase-2A-GFP Report Cell Line-MDA-MB-231
Transformed from MDA-MB-231 cells by lentivirus, expressing the firefly luciferase gene III and enhanced GFP fluorescent marker. The Luciferase and GFP was co-expressed under the same suCMV promoter as separated two proteins(not as fusion). The Puromycin marker was expressed under Rsv promoter.Each cell demonstrated strong GFP Fluorescent signal and high level of luminescence signal via luciferase assay. Note: this is pooled stable ell population, not originated from a single cell colony. Thus you will observe the uneven GFP signal intensity amount cells.