Mouse Renal Mesangial Cells
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Catalog number: 870 - ABC-TC3935
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
ABC-TC3935
Mouse Renal Mesangial Cells
Mouse Renal Mesangial Cells (MRMC) are isolated from mouse kidneys. Mouse Mesangial Cells are cryopreserved immediately after purification and delivered frozen. MRMC are guaranteed to further expand for 10 population doublings.
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ABC-TC4209
Rat Renal Mesangial Cells
Rat Renal Mesangial Cells (RRMC) are isolated from rat kidneys. Rat Mesangial Cells are cryopreserved immediately after purification and delivered frozen. RRMC are guaranteed to further expand for 15 population doublings in the condition provided by us.
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ABC-TC3784
Human Renal Mesangial Cells
Renal mesangial cells (RMC) are perivascular pericytes located within the central portion of the glomerular tuft between capillary loops. Mesangial cells have a variety of functions including synthesis and assembly of the mesangial matrix, endocytosis and processing of plasma macromolecules, and control of glomerular hemodynamics via mesangial cell contraction or release of vasoactive hormones. Mesangial cell proliferation and matrix overproduction are the predominant pathological features of many forms of glomerulonephritis, such as IgA nephropathy, lupus nephropathy, and diabetic nephropathy and frequently precedes the increase of extracellular matrix in the mesangium and the development of glomerulosclerosis. As proliferation and matrix synthesis/degradation in vitro are regulated by cytokines and growth factors, cultured cells are an ideal tool for studying pathophysiological events such as mesangial expansion, scarring, and glomerulosclerosis.HRMC from Gentaur Research Laboratories are isolated from human renal tissue. HRMC are cryopreserved after purification and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HRMC are characterized by immunofluorescent method with antibodies to fibronectin, Thy-1, and smooth muscle actin. HRMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRMC are guaranteed to further expand for 15 population doublings at the conditions specified by Gentaur Research Laboratories.
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