Mitotane
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quantity
Produktdetaljer
Katalognummer: 931 - T1199-10mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10mg
Parameters
| Additional information | SMILES: ClC(Cl)C(c1ccc(Cl)cc1)c1ccccc1Cl; Formula: C14H10Cl4 |
|---|
HY-13690
Mitotane
Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[1][2][3][4].
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