Lymphocytic choriomeningitis
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Catalog number: 597 - Oneq-V369-OneqV36950R
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: Oneq-V369-50R
NCP0160
Lymphocytic choriomeningitis mammarenavirus Nucleocapsid Protein（LCMV-NP）
Lymphocytic choriomeningitis virus (LCMV) is an arenavirus, discovered by Armstrong and Lillie in 1933 that chronically infects small rodents. Humans can be infected by direct contact with rodents or their fomites, or by inhaling aerosolized particles. In immunocompetent adults, LCMV infection leads to an influenza-like illness or aseptic meningitis that usually resolves spontaneously; infection can also be asymptomatic. When women are infected during pregnancy, the virus can be transmitted to the embryo or fetus transplacentally. Infection causes risk for miscarriage; in utero fetal death; fetopathy, including severe central nervous system or ocular malformations; and severe neurologic sequelae. Little is known about the incidence and prevalence of LCMV.