The RARα Reporter (Luc)-HEK293 Cell Line contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARα (NM_000964).
The RARβ Reporter (Luc)-HEK293 cell line contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARβ (accession # P10826-2).
The RARγ Reporter (Luc)-HEK293 cell line contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARγ (accession #P13631-1).
The TEAD Reporter andndash; MCF7 cell line contains the firefly luciferase gene under the control of TEAD responsive elements stably integrated into the human breast cancer cell line, MCF7. Inside the cells, basal unphosphorylated YAP/TAZ remains in the nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter by the activators of the Hippo pathway.
The ARE Reporter andndash; Hep G2 cell line is designed to monitor Nrf2 antioxidant response pathway. The cell contains a firefly luciferase gene under the control of ARE (antioxidant response element) stably integrated into Hep G2 cells.
Transformed from human human pancreatic cancer cell line, CFPAC-1 adhesive epithelial cell, using lentivirus expressing firefly luciferase 3 gene. The Luciferase was expressed under the enhanced EF1a promoter. The Puromycin marker was expressed under Rsv promoter. The cell line demonstrates high level of bioluminescence signal via firefly luciferase assay.
Transformed from HEK293 cells, expressing the firefly luciferase gene. Luciferase was expressed under CMV promoter, A Blasticidin antibiotic marker was expressed under Rsv promoter. The cell constitutively express Luciferase enzyme.