Immortalized Mouse Dermal Papilla Cells (iDP6)

T0720

Immortalized Mouse Dermal Papilla Cells (iDP6)

6041 €

ABC-TC3624

Human Follicle Dermal Papilla Cells

Human follicle dermal papilla cells are located in the dermal papilla at the base of hair follicles. Embedded in a laminin and collagen IV rich extracellular matrix, they are essential for induction and maintenance of hair growth. Since these cells express androgen receptors, they represent a well-suited model system for androgen-related research. Gentaur offers Human Follicle Dermal Papilla Cells (HFDPC) produced at Gentaur's cell culture facility from normal human dermis of the lateral scalp. Information on donor hair and skin color is available for each lot.Shortly after isolation, all Gentaur Human Follicle Dermal Papilla Cells are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopre -served cells that have been thawed and cultured for three days at Gentaur.

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ABC-TC3633

Human Hair Dermal Papilla Cells

The dermal papilla is a highly active group of cells. It is derived from the dermis mesenchyme, located at the base of the hair follicle. The dermal papilla is implicated in controlling the hair growth cycle; dermal papilla cells are capable of inducing follicle development from the epidermis and the production of hair fiber. Early passage dermal papilla cells can induce hair growth in vivo, but, upon further culturing, this property is lost. Hair growth is tightly regulated by the epithelial-mesenchymal interaction of hair follicle cells, for example, IFN beta secreted from dermal papilla cells inhibits the growth of outer root sheath cells in cultured. The survival of dermal papilla cell is also regulated by signal transduction pathways, activating both ERK and Akt promote dermal papilla cell survival. HHDPC from Gentaur Research Laboratories are isolated from dermal papilla of human hair follicles. HHDPC are cryopreserved at passage one culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HHDPC are characterized by their mesenchymal cell morphology and immunofluorescent method with antibody to fibronectin and CD105. HHDPC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HHDPC are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

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MBS556009-INQUIRE

Human Dermal Microvascular Endothelial Cells

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T4964

Rat Primary Dermal Endothelial cells

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ABC-TC5479

BKS DB Mouse Dermal Lymphatic Endothelial Cells

BKS db Mouse Dermal Lymphatic Endothelial Cells are isolated from the dermal lymphatic of Mice homozygous for the diabetes spontaneous mutation (Lepr/db) manifest morbid obesity, chronic hyperglycemia, pancreatic beta cell atrophy and become hypoRIemic. BKS db Mouse Dermal Lymphatic Endothelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 2 min and incubated in Gentaur's Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells at passage 3 are detached from flasks and immediately cryopreserved in vials. Each vial contains at least 0.5×106 cells per ml. The method we use to isolate primary endothelial cells was developed based on a combination of established and our proprietary methods. These cells are pre-coated with PECAM-1 antibody, following the application of magnetic beads pre-coated with secondary antibody.

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