IMM-H007
0.01 EURAsk for quotation
On request
quantity
Produktdetaljer
Katalognummer: 931 - T9010-10mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 10mg
Parameters
| Additional information | SMILES: CC(=O)OC[C@H]1CC[C@@H](O1)n1cnc2c(Nc3cccc(O)c3)ncnc12; Formula: C18H19N5O4 |
|---|
HY-141645
IMM-H007
IMM-H007 (WS070117) is an orally active and potent AMPK (AMP-activated protein kinase) activator and TGFβ1 (transforming growth factor β1) antagonist. IMM-H007 has protective effects in cardiovascular diseases via activation of AMPK. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 degradation. IMM-H007 resolves hepatic steatosis in HFD-fed hamsters by the regulation of lipid metabolism. IMM-H007 can be used for the research of nonalcoholic fatty liver disease (NAFLD) and inflammatory atherosclerosis[1][2][3].
363.7 €
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