IL-6 Leeporter NIH 3T3 Cell Line
11308.25 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS668856-5x1Vial
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 5x1Vial
Parameters
| Storage and shipping | Immediately upon receipt, store in liquid nitrogen.;;Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.;;Shipping Note: Product is available for shipment in the United States, Canada and European countries. Please inquire for shipment to other countries. |
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| Storage and shipping | With |
RC1016
IL-6 Luciferase Reporter-NIH 3T3 Cell Line
The IL-6 Luciferase Reporter cell line is a stably transfected NIH 3T3 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the IL-6 promoter. As a pleiotropic cytokine, interleukin 6 (IL-6) has pro- and anti-inflammatory roles which is not only involved in normal functions of the immune system, hematopoiesis and metabolism but also involved in the pathogenesis of metabolic and cardiovascular diseases. IL-6 gene induction is generally regulated by several transcription factors that activate the consensus sequences in the IL-6 promoter region, which include AP-1, C/EBP-beta and NF-kB in response to various proinflammatory cytokines, growth factors, and pathogen-associated molecular patterns such as Toll-like receptor (TLR) ligands. The IL-6 induction by lipopolysaccharide (LPS), the TLR4 ligand, is shown in Figure 1.
2947.2 €
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