Human TLR9 Reporter Cell Line-HEK293
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Catalog number: 870 - ABC-RC0060
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
ABC-RC0060
Human TLR9 Reporter Cell Line-HEK293
Human TLR9 Reporter Cell Line is a stably transfected HEK 293 line which expresses full-length human Toll-like receptor 9 (TLR9) with no epitope tag.
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60685
TLR9/ NF-κB Reporter - HEK293 Recombinant Cell Line
Recombinant HEK293 cell expressing firefly luciferase gene under the control of NF-κB response elements with constitutive expression of human TLR9 (Toll-like receptor 9, also been designated as CD289, a member of the toll-like receptor (TLR) family. GenBank Accession No. NM_017442)
2537.63 €
RC1031
TLR9/NF-kB Luciferase Reporter-HEK293 Cell Line
The TLR9/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 9 (TLR9) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. TLR9 is one of the key innate immune receptors. Functional activity of the cell line has been validated by TLR9 ligand assay, in which upon activation by CpG, TLR9 quickly initiates downstream signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).
10077.78 €
RC1002
AP-1 Luciferase Reporter-HEK293 Cell Line
The AP-1 Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the activator protein 1 (AP-1). The AP-1 transcription factors are homo- or hetero-dimers that consist of proteins belonging to a group of structurally and functionally related members of the Jun family (c-Jun, JunB and JunD), the Fos (c-Fos, FosB, Fra-1 and Fra-2) and the subfamilies of ATF (ATFa, ATF-2 and ATF-3) and JDP (JDP-1 and JDP-2). The AP-1 induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figure 1.
2976.67 €
RC1003
MIP-2 Luciferase Reporter-HEK293 Cell Line
The MIP-2 Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the MIP-2 promoter. Macrophage inflammatory protein 2 (MIP-2) is a small cytokine that belongs to the C-X-C chemokine family and is also known as CXCL2. MIP-2 is one of the major proinflammatory cytokines, which is induced by innate immune receptors such TLRs and Nods, and also mediates LPS-induced osteoclastogenesis. The MIP-2 induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figures 1.
2976.67 €
RC1005
TNF-alpha Luciferase Reporter-HEK293 Cell Line
The TNF-alpha Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimer's disease. The TNF-alpha induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figure 1.