Human Putative peptide YY-3 (PYY3) ELISA Kit

Human Putative peptide YY-3 (PYY3) ELISA Kit

1063.5 EUR

1063.5 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 749 - KTE61011-96T

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

AbbkineGentaur

Storlek: 96T

Parameters

Additional informationPeptide YY(3-36) , a Y2R agonist, is released from the gastrointestinal tract postprandially in proportion to the calorie content of a meal. PYY(3-36) also inhibits food intake in mice but not in Y2r- mice, which suggests that the anorectic effect requires the Y2R. Peripheral administration of PYY(3-36) increases c-Fos immunoreactivity in the arcuate nucleus and decreases hypothalamic Npy messenger RNA. Intra-arcuate injection of PYY(3-36) inhibits food intake. PYY(3-36) also inhibits electrical activity of NPY nerve terminals, thus activating adjacent pro-opiomelanocortin (POMC) neurons. In humans, infusion of normal postprandial concentrations of PYY(3-36) significantly decreases appetite and reduces food intake by 33% over 24 h. Thus, postprandial elevation of PYY(3-36) may act through the arcuate nucleus Y2R to inhibit feeding in a gut-hypothalamic pathway.
Storage and shippingStorage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.