Catalog number: 535 - cAP-0029
Product Category: Business & Industrial > Science & Laboratory
Size: 1Frozen Vial
ABC-FC0035
GFP-HPlMVPCs are Puromycin resistant HPlMVPCs isolated from normal human placental tissue, after infected GFP expressing lentiviral particles. The cells are shipped in frozen vials (the cells are provided @ passage 3). Pericyte Growth Medium is recommended for cell culture and these cells have a minimum average population doubling levels 12 when cultured following the detailed protocol described below.
ABC-TC5503
Brain Vascular Pericytes (BVP) are perivascular cells that are closely associated with the endothelium of capillaries and other small vessels. BVP, located between endothelial cells and astrocytes in the brain, communicate with other cells by extending long cytoplasmic processes which wrap around the capillaries. BVP participate in a variety of processes including angiogenesis, endothelial cell survival, regulation of capillary blood flow, and establishment and maintenance of the blood-brain barrier. Pericyte dysregulation has been linked to several pathological conditions such as hypertension, diabetic retinopathy, atherosclerosis, multiple sclerosis, Alzheimer’s disease, and tumor angiogenesis. The unique and diverse functions of BVP make them novel candidates for cell therapy in regenerative medicine. Cultured primary mouse BVP (MBVP) are a useful in vitro model for understanding the molecular mechanisms of blood-brain barrier regulation and for studying a wide variety of central nervous system diseases.