
Katalognummer: 749 - KTE61353-48T
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 48T
| Additional information | Autophagy cargo receptor encoded by NBR1 was originally identified as an ovarian tumor antigen monitored in ovarian cancer. Autophagy cargo receptor contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. |
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| Storage and shipping | Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice. |

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