Human Mobilized Peripheral Blood Mononuclear Cells
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Catalog number: 870 - ABC-TC3900
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
ABC-TC3900
Human Mobilized Peripheral Blood Mononuclear Cells
These Peripheral Blood Mononuclear Cells are collected using the COBE Spectra apheresis machine (90% of the cells are Mononuclear Cells). These PBMCs products have been depleted of red blood cells and platelets.
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ABC-SC0088T
HighQC™ Human Mobilized Peripheral Blood Mononuclear Cells
Human Peripheral Blood Mononuclear Cells (PBMC) are blood cells with a single round nucleus. These cells include lymphocytes (T, B and NK cells), monocytes and dendritic cells. Mononuclear cells are parts of the immune system which is critical for cell-mediated and humoral immunity. Mobilized peripheral blood is collected after the donor is treated with mobilization agent such as G-CSF. Such treatment mobilizes blood stem cells that are normally reside in the bone marrow to enter the blood stream. The content of CD34+ stem cells in the blood is therefore the most important parameter of graft quality. The optimal CD34+ cell dose is widely accepted to be 5 × 106/kg. Particularly, the more primitive CD34+/CD38-subset has been shown to have high self-renewal and repopulation capability. Stem cell mobilization also affects the properties of other components of the graft such as T lymphocytes and NK cells. Gentaur Human Mobilized PBMCs are isolated from healthy donors that have been mobilized with GCSF collected in acid-citrate-dextrose formula A (ACDA) as an anticoagulant. All donors must be tested negative for HBV, HCV and HIV and are IRB consented.
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ABC-TC3707
Human Mobilized Peripheral Blood Mononuclear Cells, CD34 Depleted
CD34 is a well-known marker for primitive and bone marrow-derived progenitor cells, especially for hematopoietic and endothelial progenitors. Gentaur offers CD34+ progenitor cells in a phenotypically undifferentiated state. The progenitor cells are derived from the peripheral blood of healthy donors that have undergone G-CSF mobilization. Progenitor cells contain two main cellular subpopulations, hematopoietic and endothelial progenitor cells. CD34+ progenitor cells are suitable for a series of studies for directed differentiation into more committed types of blood cells and endothelial lineages. Immediately after isolation, the freshly prepared CD34+ progenitor cells are cryopreserved.
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ABC-TC4357
Human Cystic Fibrosis Peripheral Blood Mononuclear Cells
Cystic fibrosis is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. Clinical data may include: Medication (current and historical), Disease Severity, lung Function Test (FEV1%), Sweat Test.
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ABC-TC4358
Human Stomach Cancer Peripheral Blood Mononuclear Cells
Included Diagnoses: Adenocarcinoma (including all subtypes) and Squamous Cell Carcinoma (including all subtypes), Neuroendocrine tumors of the stomach, Carcinoma of the stomach.
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ABC-TC4359
Human Ankylosing Spondylitis Peripheral Blood Mononuclear Cells
Ankylosing Spondylitis is a form of arthritis that causes inflammation of the spinal joints (vertebrae), lead to severe, chronic pain. Clinical data may include: Medication (current and historical), Disease Severity.