Human FLT3 Protein, hFc-His Tag

E33P100007

Human FLT3 Protein, hFc-His Tag

487.5 €

MBS8575065-001mg

Human FLT3 Protein, hFc-His Tag

573.88 €

MBS8575065-5x001mg

Human FLT3 Protein, hFc-His Tag

1740.5 €

MBS4160146-5x001mg

Recombinant Human FLT3 (N-GST tag)

3098.38 €

Z500147

Recombinant Human FLT3 (N-GST tag)

FLT3 is a receptor tyrosine kinase that has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors . FLT3 consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. FLT3 is the most frequently mutated gene in cases of acute myelogenous leukemia (AML). About 30 to 35% of patients have either internal tandem duplications (ITDs) in the juxtamembrane domain or mutations in the activating loop of FLT3 . The consequence of either FLT3-ITD or activating loop mutations is the constitutive activation of the tyrosine kinase activity.

671 €

IMP-661

Recombinant Human FLT1 protein, C-hFc tag

Recombinant Proteins

800 €