Katalognummer: 870 - ABC-TC3606
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 1 vial
ABC-TC3606
The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. Keratinocytes are the cells of stratified squamous epithelia. It is so named because its most abundant protein is keratin. Keratinocyte divide and are thus generated in the basal layer of the epidermis; this division is followed by a programmed death as they produce keratin and move up to the surface of the epidermis. Keratinocyte proliferation, differentiation, and apoptosis are complex and carefully choreographed processes. Besides the protective function, keratinocytes also play a central role in tissue homeostasis, wound healing, cancers, and skin-based gene-therapy. Human keratinocytes express adhesion molecules and cytokines indicating their participation in skin innate immunity and homeostasis in vivo. HEK-n from Gentaur Research Laboratories are isolated from neonate human epidermal tissue. HEK-n are cryopreserved on primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HEK-n are characterized by immunofluorescent method with antibodies to cytokeratine-18 and -19. HEK-n are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEK-n are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories.
ABC-TC3985
Neonatal Human Epidermal Keratinocytes (NHEK) are cultured by first, isolating the keratinocytes from the epidermis of the neonatal skin and then, establishing a primary keratinocyte culture. Upon completion of the primary culture, the cells are harvested, aliquoted into individual vials, and placed in liquid nitrogen storage until shipment. This product has been thoroughly tested and found to be free of the HIV Type I, Viral Hepatitis Type B and C, mycoplasma, bacteria, yeast, and fungi.
ABC-TC3961
Normal Human Epidermal Keratinocytes (NHEK) have longer guaranteed life spans than KGM or KGM-2 cells with ≥18 total population doublings for Adult cells and ≥20 population doublings for neonatal cells.