Human Epidermal Keratinocytes, Foetal
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Catalog number: 870 - ABC-TC3603
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
ABC-TC3603
Human Epidermal Keratinocytes, Foetal
Human Epidermal Keratinocytes (HEK) are primary cells isolated from normal human neonatal foreskin or adult skin. They are cryopreserved at the end of primary culture and can be cultured and propagated at least 16 population doublings.
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ABC-TC4130
Rat Epidermal Keratinocytes
Rat Epidermal Keratinocytes (REK) are derived from the skin of normal Sprague Dawley rats. They are cryopreserved at the end of primary culture. These epithelial cells proliferate well when thawed and plated from cryopreservation.
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ABC-TC3604
Human Epidermal Keratinocytes, Adult
The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. Keratinocytes are the cells of stratified squamous epithelia. It is so named because its most abundant protein is keratin. Keratinocyte divide and are thus generated in the basal layer of the epidermis; this division is followed by a programmed death as they produce keratin and move up to the surface of the epidermis. Keratinocyte proliferation, differentiation, and apoptosis are complex and carefully choreographed processes. Besides the protective function, keratinocytes also play a central role in tissue homeostasis, wound healing, cancers, and skin-based gene-therapy. Human keratinocytes express adhesion molecules and cytokines indicating their participation in skin innate immunity and homeostasis in vivo. HEK-a from Gentaur Research Laboratories are isolated from adult human epidermal tissue. HEK-a are cryopreserved on primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HEK-a are characterized by immunofluorescent method with antibodies to cytokeratine-18 and -19. HEK-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEK-a are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories.